Going Tubular in the Rostral Migratory Stream: Neurons Remodel Astrocyte Tubes to Promote Directional Migration in the Adult Brain
نویسندگان
چکیده
Newly generated neuroblasts from the subventricular zone of the adult brain migrate as neuronal chains within a network of astroglial tubes in the rostral migratory stream. This highly directed, rapid migration channels new neurons to the olfactory bulb. In this issue of Neuron, Kaneko et al. demonstrate that migrating neurons dynamically remodel the morphology and organization of astroglial tubes to promote long distance, directional migration of neurons in the adult brain.
منابع مشابه
The Role of Astrocytes in the Generation, Migration, and Integration of New Neurons in the Adult Olfactory Bulb
In mammals, new neurons in the adult olfactory bulb originate from a pool of neural stem cells in the subventricular zone of the lateral ventricles. Adult-born cells play an important role in odor information processing by adjusting the neuronal network to changing environmental conditions. Olfactory bulb neurogenesis is supported by several non-neuronal cells. In this review, we focus on the r...
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عنوان ژورنال:
- Neuron
دوره 67 شماره
صفحات -
تاریخ انتشار 2010